Immune System / Vaccines News

In Overweight And Obese Adults A Diet Rich In Slowly Digested Carbs Reduces Markers Of Inflammation

Among overweight and obese adults, a diet rich in slowly digested carbohydrates, such as whole grains, legumes and other high-fiber foods, significantly reduces markers of inflammation associated with chronic disease, according to a new study by Fred Hutchinson Cancer Research Center. Such a "low-glycemic-load" diet, which does not cause blood-glucose levels to spike, also increases a hormone that helps regulate the metabolism of fat and sugar. These findings are published online ahead of the February print issue of the Journal of Nutrition.

Identification Of Protein Changes In Early-Onset Alzheimer's

With a lack of effective treatments for Alzheimer's, most of us would think long and hard about whether we wanted to know years in advance if we were genetically predisposed to develop the disease. For researchers, however, such knowledge is a window into Alzheimer's disease's evolution.

Understanding the biological changes that occur during the clinically "silent" stage - the years before symptoms appear - provides clues about the causes of the disease and may offer potential targets for drugs that will stop it from progressing.

Possible Link Between Autism, Abnormal Immune System Characteristics And Novel Protein Fragment

Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry and the Silver Child Development Center.

The study, conducted with mouse models of autism, suggests that elevated levels of an APP fragment circulating in the blood could explain the aberrations in immune cell populations and function - both observed in some autism patients. The findings were recently published online in the Journal of the Federation of American Societies for Experimental Biology.


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