Cancer / Oncology News

Researchers Find MK1775 Active Against Sarcomas

MK 1775, a small, selective inhibitor molecule, has been found to be active against many sarcomas when tested by researchers at Moffitt Cancer Center in Tampa, Fla. Their findings, recently appearing in Molecular Cancer Therapeutics, published by the American Association for Cancer Research, suggest that a badly needed new agent against sarcomas especially sarcomas affecting children may be at hand.

Researchers Find New Path To Control Tumor Growth

New evidence by University of Alabama at Birmingham researchers that specific electromagnetic fields can safely block the proliferation of cancer cells and tumor growth may help refine a new, targeted therapy without any collateral damage.

Very low levels of amplitude-modulated radiofrequency electromagnetic fields block cancer-cell growth in a tumor- and tissue-specific fashion, says Boris Pasche, M.D., Ph.D., director of the UAB Division of Hematology and Oncology. Pasche and a research team led by Jacquelyn Zimmerman, graduate student in the UAB Medical Scientist Training Program, conducted studies with cancer cells, replicating the treatment conditions in patients with cancer. The results were published in the Dec.1, 2011, online version of the British Journal of Cancer.

Breast Cancer Progression Halted By Gene

Newly published research explores the role of 14-3-3sigma in tumour suppression.

New research out of McGill University's Goodman Cancer Research Centre provides compelling new evidence that a gene known as 14-3-3sigma plays a critical role in halting breast cancer initiation and progression. The study, led by the Dept. of Biochemistry's William J. Muller, was published online in the journal Cancer Discovery.

The discovery of this new target points to novel therapies that eventually could slow or stop breast cancer progression. Muller also says that this gene is likely a major player in a number of other types of cancer.

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