Cancer / Oncology News

Is Oxidative Stress Less Harmful Than Suspected?

Arterial calcification and coronary heart disease, neurodegenerative diseases such as Parkinson's and Alzheimer's, cancer and even the aging process itself are suspected to be partially caused or accelerated by oxidative stress. Oxidative stress arises in tissues when there is an excess of what are called reactive oxygen species (ROS). "However, up to now, nobody was able to directly observe oxidative changes in a living organism and certainly not how they are connected with disease processes," said Associate Professor (PD) Dr. Tobias Dick of DKFZ. "There were only fairly unspecific or indirect methods of detecting which oxidative processes are really taking place in an organism."

Tumor-Targeting Compound Points The Way To New Personalized Cancer Treatments

One major obstacle in the fight against cancer is that anticancer drugs often affect normal cells in addition to tumor cells, resulting in significant side effects. Yet research into development of less harmful treatments geared toward the targeting of specific cancer-causing mechanisms is hampered by lack of knowledge of the molecular pathways that drive cancers in individual patients.

Patient Receives First Prescription For FDA-Approved Brain Tumor Treatment

The University of Illinois Hospital is the first center in North America to prescribe a new FDA-approved treatment for patients with the most common and aggressive type of brain tumor, glioblastoma multiforme, or GBM.

The hospital is one of the first centers in the U.S. to receive training and certification to treat patients with recurrent GBM with a new therapy called Tumor Treating Fields. This novel, non-invasive therapy is provided using a portable device, the NovoTTF-100A System made by Novocure, which uses alternating electrical fields to disrupt the rapid cell division exhibited by cancer cells.


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