Cancer / Oncology News

A New Way To Target Cancer Through Manipulating A Master Switch Responsible For Cancer Cell Growth

Scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth.

The findings, published in the journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.

Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumour. These proteins are vascular growth factors like VEGF - the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.

Understanding How Brain Tumors Invade

Scientists have pinpointed a protein that allows brain tumors to invade healthy brain tissue, according to work published this week in the Journal of Experimental Medicine*.

40% of a common but deadly type of brain tumor - called glioblastoma multiforme (GBM) - have mutations in a gene that encodes a protein called epidermal growth factor receptor (EGFR). These mutations result in hyper-activation of the protein.

A team led by Frank Furnari of the Ludwig Institute for Cancer Research at University of California, San Diego now finds that excessive EGFR signals ramp up expression of a protein called GBP1. Without GBP1, normally invasive GBM cells formed much less infiltrative tumors in the brains of mice.

Dana-Farber Offers Healthy Holiday Recipes And Food Tips To Fight Cancer With Your Fork This Holiday Season

The holidays are in full swing and festive food is everywhere. Some are naughty, some are nice, and some may even help fight cancer.

"While these so-called holiday foods are delicious to eat, they can also have the added bonus of containing cancer-preventing nutrients," says Stephanie Meyers, MS, RD/LDN, a nutritionist at Dana-Farber Cancer Institute in Boston. Meyers and her colleagues have put together a list of foods and recipes that definitely belong on the "good" list this holiday season.

Go nuts

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