Alcohol / Addiction / Illegal Drugs News

Leading Alcohol Researchers To Discuss Alcohol's Effects On Gene Functions

Leading alcohol researchers from the United States and Canada will discuss their latest findings at an all-day meeting Nov. 18 at Loyola University Chicago Stritch School of Medicine.

Scientists will discuss the often negative effects that alcohol can have on how genes function in cells. Such changes are passed along to future generations of cells. These modifications, known as epigenetic changes, do not involve changes in the DNA sequence.

Much of the discussion will revolve around epigenetic changes caused by alcohol, especially two key events in the expression of genes -- DNA histone deacetylation and DNA methylation.

A Combination Of 2 Treatments Effective For Severe Alcoholic Hepatitis

Acute alcoholic hepatitis is one of the most serious forms of alcoholic liver disease, affecting individuals with chronic excessive alcohol consumption, which generally equates to more than 50 grams of alcohol per day (roughly five drinks), over a period of more than three to six months. The disease is characterized by liver failure (hepatic insufficiency) and acute jaundice (icterus), which may induce a coma through liver failure (hepatic encephalopathy) and an ensuing death rate of between 40-45% within the first six months. Conventional treatment involves stopping alcohol consumption (alcohol abstinence) and administering cortisone (corticosteroid therapy over a one-month period) to fight the highly inflammatory nature of the disease.

New Study Finds Bisexual Women, More Likely Than Bisexual Men, To Be Depressed And Abuse Alcohol

Bisexual women are more likely than their male counterparts to suffer from depression and stress and to binge-drink, according to a new national study led by George Mason University researcher Lisa Lindley.

Bisexual women also are at greater risk to smoke and be victimized, the research finds.

"Why?" Lindley wonders. "That's what we keep asking."

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